Okay I will try to make this short. This is my first post. I am 43 and was diagnosed with Narcolepsy (I did the MSLT) almost two years ago by a sleep doctor who did not seem up to date on treatments nor on Narcolepsy itself. He wanted me to take Ritalin, which at first I refused to do, but after 5 months I felt desperate enough to try. In short it was horrible and made me feel worse, so I immediately stopped. I go to a naturopath doctor as well as traditional doctors and it was actually this naturopath who originally suggested the sleep test... others kept saying depression and I was certain I was not clinically depressed. About a year ago after my narcolepsy diagnosis, she had a sample of Deplin and thought I should give it a try. Deplin is for depression, but she just thought it might be worth trying. The short of this is that the Deplin helps to clear the fog. I am still tired and I still need to take naps, but the Deplin definitely makes a difference enough so I can actually focus. A prime example is that I sometimes acquire contract work that is research on the computer. Pre-Deplin, I could barely get through an hour before I had to give in and lie down for a nap. Post-Deplin, I can get through 3-4 hours depending on how stimulating the research is. I would never say it gives me energy (nothing does) and I am still sleepy, but I can function so much better than before.
Deplin is L-Methylfolate, a prescription medical food (is it is basically the form of folate that can pass through the blood-brain barrier, helping to create serotonin, etc). My naturopath has to write a prescription for it. It is fairly new and is not covered by my insurance, so I buy it through Brand Direct Health for about $50/month.
Please do your own research, but I would love to know if this helps others. I have never been very good at taking pills everyday (vitamins, etc), but I take this everyday. I could feel a difference within a few days and it got better over time.
Oh and I meant to say I tried a generic L-Methylfolate and it did not work. An according to some pharmacies a generic for Deplin doesn't exist. So if you try it, go through Brand Direct.