Just started Xyrem this week and have had 2 nights on 2.25 mg. Everything I've read is that it can take up to a month for it to really start to work and thats it critical to stick to the schedule to get the best benefits. I've been setting my alarm for 4 hours after my first dose and have been waking up a little less than 2 1/2 hours after I take it. I know that I could take that 2nd dose after 2 1/2 hours of sleep but that would mean I'd be done with my two doses and wake up after only 5 hours of sleep and at 3am. Last night I woke up after 2 1/2 hours, went back to sleep until it had been the full 4 and then woke up 2 1/2 hours after the second dose and went back to sleep.
Has anyone had a similar experience? Does the "extra" sleep I'm getting, like going back to sleep after I've woken up from my 2nd dose have any impact on this process or a negative impact on establishing a schedule? I know the first reaction may be to increase the dosage. My Rx is set to increase to 3 mg after 2 weeks but I really want to be careful about increasing my dosage and am hoping that this small dosage can work for me to limit side effects and sodium intake. Any suggestions?