In the next few weeks, I will be switching to xyrem to combat my Narcolepsy without cataplexy. I was just wondering if anyone could tell me what I can expect in terms of side effects and things like that. I am currently taking 350 mg of Nuvigil ( 200mg in AM, 150 mg at noon). Ive found it to be significantly less effective compared to when I started 2 years ago. Also I was wondering if anyone takes any additional medications with xyrem. I currently take 150mg of Pristiq, 2mg of Klonopin, and 1mg of Halcion to combat Anxiety and Anxiety related Insomnia. It would be great if I could eventually stop these medications. Any advice is much appreciated.
Posted 13 July 2013 - 07:29 AM
How long have you been taking klonopin? Do you take it every night? Have you been instructed to discontinue it before starting Xyrem. It is a long acting benzodiazepine (sedative hypnotic) and is contraindicated with Xyrem because both suppress respiration.
Klonopin discontinuation requires a long slow taper. I was on 1.5 mg and it took me 6 months to get off it. I was not informed that there was a withdrawal syndrome associated with benzo withdrawal.
Consider this as a resource if you will be discontinuing klonopin: http://recovery-road.org/
Posted 13 July 2013 - 11:16 AM
We have not talk about the discontinuation of any medications I currently take. I am aware of the extremely long (30+ hr) half life of clonazepam. I take it currently for Panic Disorder, so I dont know if I should talk with my doc about changing or discontinuing the use of Benzos all together. I am obviously currently on two different benzos that serve their purposes, but the Halcion is only taken PRN so it is less of a concern for me.
Posted 17 July 2013 - 07:18 AM