Effexor and provigil
Posted 20 December 2007 - 07:56 PM
Posted 15 January 2008 - 08:10 AM
THE LACK OF SLEEP AT NIGHT. THE EFFEXOR CALMS THE BODY DOWN TO GET THE REST IT NEEDS AT NIGHT. I WAS PUT ON PROVIGAL BECAUSE OF THE EFFEXOR KIND OF HANGS ON FOR AWHILE DURING THE DAY. I HAVE ALWAYS TAKEN MY EFFEXOR AT NIGHT. I HAVE NEVER TAKEN IT DURING THE DAY. BUT CAN HONESTLEY SAY THAT THE COMBO HAS CHANGED MY LIFE FOR THE BETTER.
PS CAN YOU TELL ME WHAT YOUR DOCTOR SAID THE COMBO TOGETHER WOULD DO FOR YOU
Posted 15 January 2008 - 10:55 AM
Effexor is now available in generic form. :-)
I've learned a few things through the years:
-Effexor enhances both serotonin and norepinephrine, where the SSRIs work primarily on serotonin. It makes norepinephrine more available; this is what reduces cataplexy and increases wakefulness in PWN with cataplexy.
-Since wakefulness is not desirable at night, the immediate release form works better for me than the XR. The XR form increases my hallucinations (HH) and sleep paralysis (SP) at night.
-Because the XR version works over a longer period than the IR form, I would have needed a higher dose of XR (possibly double) in order to control my cataplexy. My doc accidentally called in a script for Effexor XR one month instead of IR but at the same dosage. I was less awake with the XR and within one day started experiencing cataplexy during the day. Given the effect on HH and SP, it didn't make sense to take a higher dose of XR, so I went back to the IR within a couple of days.
-I still need a daily nap in the afternoon (60-90 minutes) but I am mostly alert when awake with Effexor.
A newer medication, Strattera (approved for ADHD), is strictly a norepinephrine enhancer. It can be taken with Effexor for greater wakefulness, although it lasts for a much longer time than Effexor. I take it occasionally, esp. when I need to drive a distance. I have to take it first thing in the morning or it will detract from my nighttime sleep.
Effexor and Strattera may not work for you the way it works for me. It seems to be more predictably helpful to PWN with clear-cut cataplexy.
Posted 15 April 2008 - 11:58 PM
Posted 24 April 2008 - 02:05 PM
I am haapy for those of you, though, who find this to be an effective treatment and hope we all find one sooner rather than later.