First, the obligatory CONGRATULATIONS!! That is so exciting, and I am elated for you both:O) And, THANK YOU for bravely reporting the details!!!!!! I'm so glad to see a report of a family actually dealing with this scenario successfully. Many of the threads that I have read previously were loaded with naysayers about remaining on meds during pregnancy. Their comments were very judgmental and discouraging, despite the fact that they were not really educated on the topic or going through the process themselves. I have investigated this topic a lot, because my husband and I would really like to have a second child. However, we now know that I was having severe full body cataplexy attacks before, during, and directly after labor with my first. My delivery only lasted 6 and 1/2 hours, but it was a very scary and traumatic experience because we had no clue at that point that I had narcolepsy, let alone cataplexy. They just thought I was passing out because of not eating enough, or losing too much blood, or maybe they just thought I was a wimp. I just thought it was because I delivered a 9lb 12oz baby with no drugs! Go figure... Now that we are aware of my condition, and it is being treated relatively successfully, we are really feeling that "call." I spoke to my sleep specialist on the very first visit about pregnancy, and she reassured me that there are many women that have successful pregnancies while staying on meds. I researched that claim, and the risk categories of the meds that I am currently taking (Xyrem/max dose, and Nuvigil/150mg). Turns out, Xyrem is classified in the same category as Tylenol (Class for pregnancy risk! Nuvigil is an absolute no-no though, as it presents severe teratogenic and mutagenic effects in the developing baby. That was all I needed to hear to be convinced that we could have another child. I'm pretty sure that I can deal without the Nuvigil, but the Xyrem is essential to my daily functioning. I know that I will not ever be able to be without it in order to live any semblance of a normal life. My sleep specialist did also confirm that I would have to have a scheduled c-section. I am still mentally processing that one, grieving over it actually. My first delivery was all-natural at a birth center. I had the most natural, drug free, medical intervention free pregnancy and delivery the first time around. Back then, I wouldn't even take Tylenol unless I was desperate. I have always been very adamant that child birth is not a medical ailment, but boy have the tables turned! I will have to get to the acceptance phase before actually trying for a pregnancy. I'm still getting to the acceptance phase of having to take heavy duty meds every day for the rest of my life just to feel normal:o/ But I know in the long run, a second child is what I really want. I want my son to have a sibling to share the world with; a comrade and confidant. This is way more valuable than any idealized vision of child birth. Anyway, I didn't mean to ramble or steal any of your thunder:o) However, I just wanted to confirm for others that my sleep doc said virtually the same thing as yours: 1) Get off the stimulant drugs at least a month before conception, and stay off of them throughout pregnancy. 2) Many, many women stay on Xyrem during conception and throughout their pregnancy without negative effects for the mother or baby. 3) If you are narcoleptic, cataplexy or not, you will have a scheduled c-section for delivery. 4) I can confirm from personal experience that the scheduled c-section is both extremely necessary, and in a weird way highly desirable. You will avoid the risk of complications from cataplexy, and you won't wear your body out through natural delivery. The one thing that I have not gotten a conclusive answer on, however, is whether or not you can nurse while on Xyrem. This is still one of my hang-ups. I really want to nurse. My first time around didn't go very well. I was undiagnosed at that point, and nothing was going well for me (to put it mildly). I am definitely anxious for a second chance with that. Mr. (Ms.? I don't like to assume, no offense) cmcardle74, would you please post with any information you receive about Xyrem and nursing? I would be really grateful for the information! We are planning to start trying for a baby in January, so I am amassing all of my research. Also, please continue to update us in general. You are my/our only live lead so far! Take care!